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Ampyra and Pregnancy

In animal studies on pregnancy and Ampyra (dalfampridine), the medication decreased offspring growth and survival rates when it was given to rats during pregnancy and while breastfeeding. Because of this, this medication is considered a pregnancy Category C drug, meaning it may not be safe to use in pregnant women. However, your healthcare provider may still prescribe this medicine if the benefits outweigh the risks.

Can I Take Ampyra When Pregnant?

Ampyra™ (dalfampridine) is a prescription multiple sclerosis medication. Based on the results of animal studies, it may not be safe for pregnant women to take Ampyra.

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but appear to cause harm to the fetus in animal studies.
Medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
In studies, giving high doses of Ampyra to pregnant rats and rabbits did not cause any problems in the offspring (even though the doses were high enough to cause problems in the mothers themselves). However, when Ampyra was given to the mother rats during pregnancy and while breastfeeding, offspring growth and survival were reduced.
However, it is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.

Final Thoughts

If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. He or she will consider both the benefits and risks of taking Ampyra before making a recommendation in your particular situation.
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Ampyra Medication Information

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