Aubagio Side Effects
During extensive clinical studies on Aubagio, some of the side effects that occurred most often included headaches, diarrhea, and nausea. These studies also showed that some people who use this prescription drug may develop serious reactions. Contact your healthcare provider right away if you are taking this drug and develop potentially dangerous problems, such as fever, breathing problems, or confusion.
As with any medicine, Aubagio® (teriflunomide) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Aubagio. Your healthcare provider can discuss a more complete list with you.)
Aubagio has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Aubagio were documented and then compared to the side effects that occurred in a similar group of people taking a placebo (a "sugar pill" with no active ingredients). As a result, it was possible to see what side effects occurred, how often they occurred, and how they compared to the placebo.
In these studies, the most common Aubagio side effects included:
- Headache -- in up to 22 percent of people
- Diarrhea -- up to 18 percent
- Nausea -- up to 14 percent
- An increase in certain liver enzymes (found using standard blood tests) -- up to 14 percent
- Hair loss -- up to 13 percent
- Flu-like symptoms -- up to 12 percent
- Sensations of tingling, burning, pricking, or numbness of the skin -- up to 10 percent.
Other common side effects of Aubagio, occurring in 2 percent to 9 percent of people, included:
- Upper respiratory tract infections
- Upper abdominal (stomach) pain
- Muscle and bone pain
- Bladder infection
- Stomach flu
- Cold sores
- High blood pressure (hypertension)
- Seasonal allergy
- Weight loss
- Sciatica (pain or numbness that begins in the lower back and radiates down one or both legs)
- General burning sensations
- Pain, weakness, or numbness in the hands or wrists (carpal tunnel syndrome)
- Blurred vision
- Pink eye (conjunctivitis)
- Feelings of a pounding or racing heartbeat
- Abnormally low levels of white blood cells
- Abdominal distention (stomach bloating).