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Taking Baclofen Intrathecally and Treatment Tips

Intrathecal Baclofen Dose

A specific protocol must be followed in order to determine an appropriate dose for baclofen intrathecal infusion (in which the medication is delivered directly to the spinal cord via a pump). First, a "test dose" is given to make sure that the medication is actually going to work. This is given by an injection directly into the intrathecal space around the spinal cord. If no response is seen, a second, higher test dose may be given.
The starting dose for actual use in the pump will be based on the response to the test dose. The dosage will then be gradually increased until the desired result is achieved. The "maintenance" dose may occasionally need to be adjusted, especially during the first few months of use, in order to achieve a good balance between effectiveness and undesirable side effects.
The specific way and frequency of refilling the pump reservoir will vary, depending on the particular type of pump used.

General Information on Your Dose of Baclofen

Some considerations for people taking baclofen include the following:
  • This medication comes in tablet form. It is taken by mouth usually three or four times a day.
  • Alternatively, baclofen can be given through a pump directly into the spinal cord. This method is reserved for severe cases of spasticity.
  • You can take your dose with food or on an empty stomach.
  • Make sure to take this medication at the same times each day to keep an even level in your blood.
  • For baclofen to work properly, it must be taken as prescribed. Do not suddenly stop taking this medication (see Baclofen Withdrawal).
  • If you are unsure about anything related to dosing with baclofen, please talk with your doctor, nurse, or pharmacist.
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