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Baclofen Effects and Treatment Instructions

Drug Interactions

Baclofen can potentially interact with some other medicines (see Baclofen Drug Interactions).

What If I Take an Overdose?

An overdose of baclofen can cause serious problems. If you happen to overdose on this medication, seek immediate medical attention.
(Click Baclofen Overdose for more information.)

How Should Baclofen Be Stored?

Baclofen should be stored at room temperature, away from moisture and heat. Keep this and all other medications out of the reach of children.

What Should I Do If I Miss a Dose?

If you do not take your baclofen as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.

How Does This Medication Work?

It is not fully understood exactly how baclofen works to treat spasticity. The medicine is chemically similar to gamma-aminobutyric acid (GABA), a chemical messenger in the central nervous system. The primary activity of GABA is to inhibit nerve signals, and baclofen might have actions that are similar to GABA.
Baclofen intrathecal infusion (delivered directly to the spinal cord by a pump) works to provide the medication directly to the spinal cord. This, to some extent, spares the rest of the body from side effects.

When and How to Take Baclofen

Some general considerations to keep in mind during treatment are as follows:
  • This medication comes in tablet form. It is taken by mouth usually three or four times a day.
  • Alternatively, baclofen can be given through a pump directly into the spinal cord. This method is reserved for severe cases of spasticity.
  • You can take your dose with food or on an empty stomach.
  • Make sure to take this medication at the same times each day to keep an even level in your blood.
  • For baclofen to work properly, it must be taken as prescribed.
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Baclofen Medication Information

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