The recommended dose of Extavia for treating multiple sclerosis is 0.25 mg, injected just under the skin every other day. People are generally prescribed a low dosage to start (such as 0.0625 mg) and gradually work up to the full amount after seven weeks. It may be useful to take a pain reliever before, during, or after each dosage to help prevent flu-like symptoms.
Dosing With Extavia: An IntroductionThere is only one standard dosage for Extavia® (interferon beta-1b), regardless of your age or weight. As is always the case, do not adjust this amount unless your healthcare provider specifically tells you to do so.
The recommended Extavia dose for treating multiple sclerosis (MS) is 0.25 mg, injected subcutaneously (just under the skin) every other day. This is the same as 1 mL of Extavia, if you have mixed it correctly. Typically, your healthcare provider will recommend that you start with a low dose and slowly work up to the full amount, as follows:
- Weeks one and two -- 0.0625 mg (0.25 mL once mixed)
- Weeks three and four -- 0.125 mg (0.5 mL once mixed)
- Weeks five and six -- 0.1875 mg (0.75 mL once mixed)
- Week seven and beyond -- 0.25 mg (1 mL once mixed).
Your healthcare provider may recommend taking a nonprescription pain reliever, such as Tylenol® (acetaminophen), before, at the same time, or after each Extavia injection. This can help prevent some of the flu-like symptoms, such as fever, chills, and muscle aches, common with this medication.
General Information on Your Extavia DoseSome considerations to keep in mind when taking Extavia include the following:
- Extavia comes as an injection. It is injected subcutaneously (just under the skin) every other day. You will start at a low dose and slowly work up to the full amount.
- Take this medicine at the same time each day. You may need to develop a system to remember which days you take Extavia and which days you do not.
- Each Extavia vial is for a single use only. If your dosage is less than the full vial, any unused portion must be discarded (it cannot be saved for later).
- It is best to inject the medication into areas of the skin that have a layer of fat underneath. This includes the thigh, the outer upper arm, stomach (away from the navel), or buttocks. Try to rotate the injection sites -- do not inject in the same place twice in a row.
- Make sure your healthcare provider teaches you exactly how to inject Extavia. This includes how to prepare the skin, how to prepare and mix the injection, how to inject the medication, and what to do with your used needles (this may vary, depending on local laws and regulations).
- For the medicine to work properly, it must be taken as prescribed. Extavia will not work if you stop taking it.
- If you are unsure about anything related to your dosage or Extavia dosing in general, please talk with your doctor, nurse, or pharmacist.