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Understanding How Gilenya Works and Pediatric/Off-Label Uses

How Does Gilenya Work?

It is still unclear how exactly Gilenya works to treat MS. The drug is classified as a "sphingosine 1-phosphate receptor modulator." It binds to certain receptors in the body and prevents lymphocytes from leaving the lymph nodes. This decreases the number of lymphocytes in the bloodstream. A lymphocyte is a type of white blood cell that plays an important role in the immune system.

Can Children Use It?

Gilenya is not approved for use in people younger than 18 years of age, as it has not been adequately studied in this age group.

Can Older Adults Use It?

Yes, older adults can use Gilenya. However, the medication has not been adequately studied in older adults to determine whether they will respond to the medication in the same way as younger individuals. Some older adults may be more sensitive to the side effects of this medication, and may therefore need more careful monitoring.

Off-Label Uses for Gilenya

On occasion, your healthcare provider may recommend Gilenya for something other than MS. This is called an "off-label" use. At this time, there are no universally accepted off-label uses for Gilenya.
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Gilenya Medication Information

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