How Tizanidine Works and Issues to Discuss With Your Doctor
What Should I Tell My Healthcare Provider?Prior to taking this product, talk to your healthcare provider if you have:
- Low blood pressure (hypotension)
- A slow heart rate (bradycardia)
- Liver disease, such as liver failure, hepatitis, or cirrhosis
- Kidney disease, such as kidney failure (renal failure)
- Any allergies, including to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Tizanidine and Pregnancy)
- Breastfeeding (see Tizanidine and Breastfeeding).
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription drugs, vitamins, and herbal supplements.
(Click Precautions and Warnings With Tizanidine to learn more, including information on who should not take the drug.)
How Does Tizanidine Work?Tizanidine belongs to a group of medications known as alpha-2 adrenergic agonists. It binds to and stimulates alpha-2 receptors, an action that inhibits motor neurons. This medication works centrally (in the spinal cord or brain), not directly on the muscles.